Biological Psychology 11th International Edition – Test Bank

 

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Sample Test

Chapter 3: Communication at Synapses

 

TRUE/FALSE

 

1.   Transmission of information between neurons occurs in the same way as transmission along the axon.

 

ANS:  F                    PTS:   1                    DIF:    conceptual     REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

MSC:  www

 

2.   A reflex arc consists only of sensory neurons.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

MSC:  www

 

3.   Only sensory neurons are found in a reflex arc.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

4.   Reflexive flexion and extension of a dog’s legs can still occur when the spinal cord is disconnected from the brain.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses

OBJ:   1                    TOP:   3.1 The Concept of the Synapse

 

5.   At synapses, the cell that receives the message is called the presynaptic neuron.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses

OBJ:   1                    TOP:   3.1 The Concept of the Synapse

MSC:  www

 

6.   At synapses, the cell that delivers the message is called the presynaptic neuron.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses

OBJ:   1                    TOP:   3.1 The Concept of the Synapse

 

7.   Electrical communication between neurons is faster than chemical communication within neurons.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses

OBJ:   1                    TOP:   3.1 The Concept of the Synapse

 

 

8.   Chemical communication between neurons is faster than electrical communication within neurons.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses

OBJ:   1                    TOP:   3.1 The Concept of the Synapse

 

9.   The amount of temporal summation depends on the rate of stimulation.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses

OBJ:   1                    TOP:   3.1 The Concept of the Synapse

MSC:  www

 

10.                Most excitatory post-synaptic potentials result in an action potential.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses

OBJ:   2                    TOP:   3.1 The Concept of the Synapse

 

11.                Graded potentials can be depolarizations or hyperpolarizations.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses

OBJ:   2                    TOP:   3.1 The Concept of the Synapse

 

MSC:  www

 

12.                Spatial summation is the result of synaptic inputs from different locations arriving at the same time.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses

OBJ:   2                    TOP:   3.1 The Concept of the Synapse

 

13.                Inhibitory synapses actively suppress excitatory responses.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses

OBJ:   2                    TOP:   3.1 The Concept of the Synapse

MSC:  www

 

14.                Most neurons have a spontaneous firing rate, a periodic production of action potentials even without synaptic input.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   Relationship Among EPSP, IPSP, and Action Potentials

OBJ:   3                    TOP:   3.1 The Concept of the Synapse

 

 

 

15.                Some neurotransmitters are monoamines.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse

OBJ:   2                    TOP:   3.2 Chemical Events at the Synapse

 

16.                Gases can be used as neurotransmitters.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse

OBJ:   2                    TOP:   3.2 Chemical Events at the Synapse

MSC:  www

 

17.                Neurotransmitter levels in the brain can be affected by changes in diet.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse

OBJ:   3                    TOP:   3.2 Chemical Events at the Synapse

 

18.                Most of the known neurotransmitters are synthesized from amino acids.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse

OBJ:   3                    TOP:   3.2 Chemical Events at the Synapse

 

 

19.                Most neurons release more than one kind of neurotransmitter.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

 

20.                Generally speaking, a neuron will release a greater number of neurotransmitters than what it will respond to with its own receptors.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

 

21.                Whether or not a neurotransmitter is excitatory depends on the response of the postsynaptic receptor.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

 

 

 

 

22.                Rapid changes in heart rate are probably due to the activity of ionotropic receptors.

 

ANS:  T                    PTS:   1                    DIF:    conceptual     REF:   The Sequence of Chemical Events at a Synapse           OBJ:               5         TOP:              3.2 Chemical Events at the Synapse

 

23.                Most of the brain’s excitatory ionotropic synapses use the neurotransmitter glutamate.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               5         TOP:              3.2 Chemical Events at the Synapse

KEY:  NEW

 

24.                Metabotropic synapses use a large variety of transmitters.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               8         TOP:              3.2 Chemical Events at the Synapse

 

25.                A drug that blocks the effects of a neurotransmitter is an antagonist.

 

ANS:  T                    PTS:   1                    DIF:    factual            REF:   Drug Mechanisms

OBJ:   2                    TOP:   3.1 Synapses, Drugs, and Addictions

MSC:  www

 

26.                A drug that blocks the effects of a neurotransmitter is an agonist.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   Drug Mechanisms

OBJ:   2                    TOP:   3.1 Synapses, Drugs, and Addictions

MSC:  www

 

27.                Unlike studies with animals, MDMA in humans is harmless to serotonin neurons.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   A Survey of Abused Drugs                 OBJ:    3           TOP:              3.1 Synapses, Drugs, and Addictions

 

28.                Opiates work at the pain receptors in the skin.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   A Survey of Abused Drugs                 OBJ:    4           TOP:              3.1 Synapses, Drugs, and Addictions

 

29.                Marijuana is used medically to enhance memory.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   A Survey of Abused Drugs     OBJ:    4           TOP:              3.1 Synapses, Drugs, and Addictions

MSC:  www

 

 

 

 

30.                Marijuana withdrawal is more intense than opiate withdrawal.

 

ANS:  F                    PTS:   1                    DIF:    factual            REF:   A Survey of Abused Drugs                 OBJ:    4           TOP:              3.1 Synapses, Drugs, and Addictions

 

MULTIPLE CHOICE

 

1.   Charles S. Sherrington was the first to infer the properties of which of the following?

a.

synapses

b.

the refractory period

c.

the sodium-potassium pump

d.

dendrites and axons

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

2.   ____ are specialized junctions between neurons.

a.

Nodes of Ranvier

b.

Synapses

c.

Dendrites

d.

Spines

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

3.   Specialized junctions between neurons are called:

a.

nodes of Ranvier.

b.

spines.

c.

dendrites.

d.

synapses.

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

MSC:  www

 

4.   On the basis of what evidence were the properties of synapses first inferred?

a.

the electron microscope

b.

single-neuron recordings

c.

behavioral observations

d.

PET scans

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

5.   The circuit from sensory neuron to muscle response is called:

a.

a reflex arc.

b.

a synapse.

c.

flexion.

d.

extension.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

6.   The proper order of a reflex arc is:

a.

motor neuron, sensory neuron, interneuron.

b.

sensory neuron, motor neuron, interneuron.

c.

motor neuron, interneuron, sensory neuron.

d.

sensory neuron, interneuron, motor neuron.

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

7.   Why is the speed of conduction through a reflex arc slower than the speed of conduction of an action potential along an axon?

a.

Transmission between neurons at synapses is slower than along axons.

b.

The longer an axon, the slower its velocity.

c.

Interneurons have thicker axons than other neurons.

d.

There are greater amounts of myelin involved in the reflex arc.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

8.   Sherrington deduced that transmission at a synapse must be slower than conduction along an axon. This was based on what kind of evidence?

a.

temporal summation

b.

drugs that increase or inhibit activity at synapses

c.

the speed of reflexive responses

d.

differences in diameter between axons and dendrites

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

9.   A certain weak stimulus produces no reflexive response, but a rapid repetition of that stimulus may produce such a response. What is this phenomenon called?

a.

spatial summation

b.

temporal summation

c.

saltatory conduction

d.

synaptic combination

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

10.                Sherrington found that repeated stimuli within a brief time have a cumulative effect. He referred to this phenomenon as:

a.

temporal summation

b.

spatial summation

c.

synaptic summation

d.

saltatory summation

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

MSC:  www

 

 

 

11.                Temporal summation most likely occurs with:

a.

infrequent, subthreshold excitation.

b.

rapid succession of stimuli that each exceed threshold.

c.

infrequent, inhibitory stimuli.

d.

rapid succession of subthreshold excitation.

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

12.                Which of the following statements regarding reflexes would Charles Sherrington most likely agree with?

a.

The overall speed of conduction through a reflex arc is faster than conduction along an axon.

b.

Repeated stimuli occurring within a brief time can have a cumulative effect.

c.

Each neuron physically merges with the next one.

d.

Excitatory synapses are more important than inhibitory synapses.

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

13.                To measure temporal summation in single cells, researchers:

a.

attach electrodes to the scalp.

b.

insert an microelectrode into the scalp.

c.

collect sodium and potassium ions from nearby glial cells.

d.

record depolarizations of the postsynaptic neuron.

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

 

14.                A graded depolarization is known as an:

a.

EPIP

b.

IPSP

c.

ESPN

d.

EPSP

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    1           TOP:              3.1 The Concept of the Synapse

KEY:  NEW

 

15.                Which of the following is TRUE about EPSPs?

a.

It takes two to produce an action potential.

b.

They decay over time and space.

c.

They can be either excitatory or inhibitory.

d.

They occur because potassium gates open.

 

 

ANS:  B                    PTS:   1                    DIF:    51                  REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

MSC:  www

 

 

 

 

16.                An EPSP is a(n):

a.

graded depolarization.

b.

depolarization with a rebounding hyperpolarization.

c.

graded hyperpolarization.

d.

action potential in a reflex arc.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

17.                Which of the following is NOT true about EPSPs?

a.

They decay over time.

b.

Their strength decreases with distance.

c.

They operate on an all-or-none principle.

d.

They are depolarizations.

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

18.                The primary difference between an EPSP and an action potential is that:

a.

the magnitude of an action potential decreases as it travels along the membrane.

b.

EPSPs occur without sodium ions entering the cell.

c.

action potentials are always hyperpolarizations.

d.

EPSPs are subthreshold events that decay over time and space.

 

 

ANS:  D                    PTS:   1                    DIF:    conceptual     REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

19.                Depolarization is to ____ as hyperpolarization is to ____.

a.

excitation; inhibition

b.

inhibition; excitation

c.

increasing the threshold; decreasing the threshold

d.

decreasing the threshold; increasing the threshold

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

MSC:  www

 

20.                What causes an EPSP?

a.

the deactivation of cytoplasmic enzymes

b.

the opening of sodium channels

c.

the opening of potassium channels

d.

inherited paranormal psychic abilities

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

21.                Like an action potential, an EPSP results from:

a.

sodium ions entering the cell.

b.

potassium ions entering the cell.

c.

sodium ions exiting the cell.

d.

potassium ions exiting the cell.

 

 

 

 

 

 

 

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

22.                Which of the following would produce spatial summation?

a.

Present two or more weak stimuli at the same time.

b.

Start action potentials at both ends of one axon at the same time.

c.

Do not allow a flexor muscle to relax before stimulating it again.

d.

Present a rapid sequence of weak stimuli.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

MSC:  www

 

23.                Spatial summation refers to:

a.

multiple weak stimulations that occur in rapid succession.

b.

a decrease in responsiveness after repeated stimulation.

c.

multiple weak stimulations that occur at the same time.

d.

an increase in the strength of action potentials after repeated stimulation.

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

24.                What is the primary difference between temporal summation and spatial summation?

a.

Only spatial summation can produce an action potential.

b.

Spatial summation depends on contributions from more than one sensory neuron.

c.

Temporal summation produces a hyperpolarization instead of a depolarization.

d.

Spatial summation alters the response of more than one postsynaptic cell.

 

 

ANS:  B                    PTS:   1                    DIF:    conceptual     REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

25.                Simultaneous weak stimuli at different locations produce a greater reflexive response than one of the stimuli by itself. What is this phenomenon called?

a.

Sherrington’s law

b.

temporal summation

c.

spatial summation

d.

the all-or-none law

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

26.                What do temporal summation and spatial summation have in common?

a.

Both involve the activity of only two neurons.

b.

Both require a response from the brain.

c.

Both depend on a combination of visual and auditory stimuli.

d.

Both enable a reflex to occur in response to weak stimuli.

 

 

ANS:  D                    PTS:   1                    DIF:    conceptual     REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

 

 

 

27.                Temporal summation is to ____ as spatial summation is to ____.

a.

time, location

b.

EPSP, IPSP

c.

location, time

d.

depolarization, hyperpolarization

 

 

ANS:  A                    PTS:   1                    DIF:    conceptual     REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

KEY:  www

 

28.                Which of the following patterns of post-synaptic excitation will most likely result in an action potential?

a.

rapid sequence of EPSPs

b.

rapid sequence of IPSPs

c.

large number of simultaneous IPSPs

d.

large number of simultaneous IPSPs and EPSPs

 

 

ANS:  A                    PTS:   1                    DIF:    conceptual     REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

29.                When a vertebrate animal contracts the flexor muscles of a leg, it relaxes the extensor muscles of the same leg. Sherrington considered this evidence for the existence of:

a.

spatial summation.

b.

temporal summation.

c.

inhibitory messages.

d.

the delay in transmission at synapses.

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

30.                What ordinarily prevents extensor muscles from contracting at the same time as flexor muscles?

a.

the ligaments and tendons that bind them together

b.

learned patterns of coordination in the cerebral cortex

c.

inhibitory synapses in the spinal cord

d.

control of both muscles by different branches of the same axon.

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

31.                In a reflex arc, the coordination between contraction of certain muscles and relaxation of others is mediated by:

a.

glial cells.

b.

motor neurons.

c.

sensory neurons.

d.

interneurons.

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

 

 

 

32.                A normal, healthy animal never contracts the flexor muscles and the extensor muscles of the same leg at the same time. Why not?

a.

When the interneuron sends excitatory messages to one, inhibitory messages go to the other.

b.

They are mechanically connected in a way that makes it impossible for both to contract at the same time.

c.

Such coordination is learned through prenatal movement.

d.

Both muscles are controlled by branches of the same axon.

 

 

ANS:  A                    PTS:   1                    DIF:    conceptual     REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

33.                Inhibitory synapses on a neuron:

a.

hyperpolarize the postsynaptic cell.

b.

weaken the cell’s polarization.

c.

increase the probability of an action potential.

d.

move the potential closer to the cell’s threshold.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

34.                A temporary hyperpolarization is known as an:

a.

EPSP.

b.

IPSP.

c.

ISPS.

d.

EPIP.

 

 

 

ANS:  B                    PTS:   1                    DIF:    factual            R REF:           The Properties of Synapses      OBJ:    2           TOP:              3.1 The Concept of the Synapse

KEY:  NEW

 

35.                Which of the following would most likely result in an IPSP?

a.

potassium ions entering the cell

b.

sodium ions entering the cell

c.

chloride ions entering the cell

d.

chloride ions leaving the cell

 

 

ANS:  C                    PTS:   1                    DIF:    conceptual     REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

36.                Increased permeability to which of the following ions would most likely result in an IPSP?

a.

sodium

b.

potassium

c.

calcium

d.

bicarbonate

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

 

 

 

37.                An IPSP represents:

a.

the location where a dendrite branches.

b.

a gap in a myelin sheath.

c.

a subthreshold depolarization.

d.

a temporary hyperpolarization.

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

38.                Increased permeability to ____ would most likely result in an IPSP.

a.

sodium

b.

potassium

c.

calcium

d.

bicarbonate

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

39.                An EPSP is to ____ as an IPSP is to ____.

a.

hyperpolarization; depolarization

b.

depolarization; hyperpolarization

c.

spatial summation; temporal summation

d.

temporal summation; spatial summation

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

40.                Which of the following is NOT a factor in determining whether or not two EPSPs combine to reach threshold?

a.

size of the EPSPs

b.

timing between them

c.

threshold of the postsynaptic cell

d.

threshold of the presynaptic cell

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

41.                Even at rest, most neurons have periodic production of action potentials, known as the:

a.

spontaneous firing rate.

b.

excitatory firing rate.

c.

all-or-none law.

d.

Dale’s principle.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

42.                The “decision” for a neuron to fire is determined by the:

a.

number of EPSPs only.

b.

spontaneous firing rate.

c.

number of IPSPs only.

d.

ratio of EPSPs to IPSPs.

 

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

43.                The “spontaneous firing rate” of a neuron refers to:

a.

its resting potential.

b.

its rate of energy consumption.

c.

its rate of producing action potentials even when it is not stimulated.

d.

the velocity of its action potentials under normal conditions.

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    2           TOP:              3.1 The Concept of the Synapse

 

44.                Which of the following is TRUE about the spontaneous firing rates of neurons?

a.

EPSPs increase the frequency.

b.

EPSPs decrease the frequency.

c.

IPSPs increase the frequency.

d.

One EPSP equals the effect of two IPSPs.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    3           TOP:              3.1 Synapses

 

45.                What determines whether a neuron has an action potential?

a.

only the number of EPSPs impinging on an axon

b.

only the number of IPSPs impinging on the dendrites

c.

the combined effects of EPSPs and IPSPs

d.

summation effects of IPSPs

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Properties of Synapses     OBJ:    3           TOP:              3.1 Synapses

 

46.                Which one of Sherrington’s inferences about the synapse was WRONG?

a.

Transmission at a synapse is slower than transmission of impulses along an axon.

b.

Transmission at the synapse is primarily an electrical process.

c.

Synapses can be either excitatory or inhibitory.

d.

Synapses make spatial summation and temporal summation possible.

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Discovery of Chemical Transmission at Synapses                  OBJ:   1                    TOP:   3.2 Chemical Events at the Synapse

 

47.                What was the first evidence reported by T. R. Elliott suggesting that synapses operate chemically?

a.

Adrenaline mimics the effects of the parasympathetic nervous system.

b.

Adrenaline decreases heart rate.

c.

Adrenaline produces a hormone which decreases heart rate.

d.

Adrenaline mimics the effects of the sympathetic nervous system.

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Discovery of Chemical Transmission at Synapses                  OBJ:   1                    TOP:   3.2 Chemical Events at the Synapse

 

 

 

48.                Loewi demonstrated that synapses operate by the release of chemicals. He did this by:

a.

applying adrenaline directly to the heart muscle.

b.

collecting fluid from a stimulated frog’s heart, transferring it to another frog’s heart, and measuring that heart rate.

c.

measuring the speed of a dog’s reflexes while the dog was under the influence of various drugs.

d.

applying an extract of marijuana in eye drops and discovering that it dilated the pupils.

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Discovery of Chemical Transmission at Synapses                  OBJ:   1                    TOP:   3.2 Chemical Events at the Synapse

 

49.                The research that firmly established synaptic communication as chemical was:

a.

Elliot’s adrenaline mimicking sympathetic activation.

b.

Loewi’s transfer of fluid from stimulated frog hearts.

c.

Sherrington’s study of reflexes.

d.

Eccles’s measurement of IPSPs.

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Discovery of Chemical Transmission at Synapses                  OBJ:   1                    TOP:   3.2 Chemical Events at the Synapse

 

50.                After one frog’s heart has been stimulated, an extract of fluid from that heart can make a second frog’s heart beat faster. What conclusion did Otto Loewi draw from these results?

a.

Transmission at synapses is a chemical event.

b.

The sympathetic and parasympathetic nervous systems are antagonistic.

c.

Transmission at heart muscle synapses is electrical.

d.

Hormones facilitate the actions of the nervous system.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Discovery of Chemical Transmission at Synapses                  OBJ:   1                    TOP:   3.2 Chemical Events at the Synapse

 

51.                The correct sequence of chemical events at a synapse is:

a.

reuptake, release, transport, synthesis

b.

synthesis, transport, release, reuptake

c.

transport, release, reuptake, synthesis

d.

recycle, reuse, release, return

 

 

ANS:  B                    PTS:   1                    DIF:    conceptual     REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

53.                ____ are a category of chemicals including adenosine and several of its derivatives.

a.

Neuropeptides

b.

Acetylcholine

c.

Monoamines

d.

Purines

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               2         TOP:              3.2 Chemical Events at the Synapse

 

54.                What is the most unusual thing about the neurotransmitter nitric oxide (NO)?

a.

It is found only in sensory neurons.

b.

It is both excitatory and inhibitory.

c.

It is normally a poisonous gas.

d.

It is also known as “laughing gas.”

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               2         TOP:              3.2 Chemical Events at the Synapse

 

55.                Nitric oxide’s value is that it:

a.

increases blood flow to certain areas of the brain.

b.

restricts blood flow to certain areas of the brain.

c.

increases growth of microglia.

d.

decreases growth of microglia.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               2         TOP:              3.2 Chemical Events at the Synapse

 

56.                Which of the following neurotransmitters is released by active neurons to dilate the blood vessels and increase blood flow?

a.

endorphins

b.

glycine

c.

nitric oxide

d.

acetylcholine

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               2         TOP:              3.2 Chemical Events at the Synapse

MSC:  www

 

57.                In addition to influencing other neurons, ____ dilates the nearby blood vessels, thereby increasing blood flow to that area of the brain.

a.

endorphins

b.

glycine

c.

nitric oxide

d.

acetylcholine

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               2         TOP:              3.2 Chemical Events at the Synapse

 

58.                What provides the building blocks for synthesizing all neurotransmitters?

a.

substances found in the diet

b.

breakdown products of DNA

c.

breakdown products formed from other transmitters

d.

methane and ethanol

 

 

ANS:  A                    PTS:   1                    DIF:    conceptual     REF:   Chemical Events at the Synapse          OBJ:    3           TOP:              3.2 Synapses

 

59.                The basic building blocks for the majority of neurotransmitters are:

a.

amino acids.

b.

nitric oxide.

c.

sugars.

d.

carbohydrates.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               2         TOP:              3.2 Chemical Events at the Synapse

 

60.                All of the following are catecholamines EXCEPT:

a.

dopamine.

b.

serotonin.

c.

norepinephrine.

d.

epinephrine.

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               2         TOP:              3.2 Chemical Events at the Synapse

 

61.                Which of the following is NOT a catecholamine?

a.

Dopamine

b.

Epinephrine

c.

Norepinephrine

d.

Serotonin

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               2         TOP:              3.2 Chemical Events at the Synapse

 

62.                The catecholamines include:

a.

epinephrine, norepinephrine, dopamine, and serotonin.

b.

epinephrine, serotonin, and dopamine.

c.

dopamine, serotonin, and acetylcholine.

d.

epinephrine, norepinephrine, and dopamine.

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               2         TOP:              3.2 Chemical Events at the Synapse                                   MSC:   www

 

63.                A new drug is discovered that affects the activity of enzymes. Which of the following stages of synaptic transmission is most likely to be affected?

a.

Synthesis

b.

Diffusion

c.

action potential

d.

Release

 

 

ANS:  A                    PTS:   1                    DIF:    conceptual     REF:   The Sequence of Chemical Events at a Synapse           OBJ:               3         TOP:              3.2 Chemical Events at the Synapse

 

 

 

64.                What makes nitric oxide unique among neurotransmitters?

a.

It is released before the action potential occurs.

b.

It is taken back up into the presynaptic neuron.

c.

It is a gas.

d.

It is composed of amino acids.

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               3         TOP:              3.2 Chemical Events at the Synapse           MSC:   www

 

65.                What do dopamine, norepinephrine, and epinephrine share in common?

a.

They all affect the same receptors.

b.

They are all synthesized from the same amino acids.

c.

They are all released by the same neurons.

d.

They all are gases.

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               3         TOP:              3.2 Chemical Events at the Synapse

 

66.                Avoiding foods with lecithin, such as eggs and peanuts, would affect which neurotransmitter level the most?

a.

acetylcholine

b.

serotonin

c.

GABA

d.

endorphin

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               3         TOP:              3.2 Chemical Events at the Synapse

 

67.                The amino acid tryptophan is the precursor to which neurotransmitter?

a.

dopamine

b.

endorphin

c.

serotonin

d.

nitric oxide

 

 

 

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               3         TOP:              3.2 Chemical Events at the Synapse                       KEY: NEW

 

68.                After a meal that was rich in the amino acid tryptophan, which neurotransmitter level would be increased the most?

a.

dopamine

b.

endorphin

c.

serotonin

d.

nitric oxide

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               3         TOP:              3.2 Chemical Events at the Synapse

 

69.                If you eat a food containing tryptophan, what can you consume with it to increase its entry to the brain?

a.

phenylalanine

b.

carbohydrates

c.

fats

d.

thiamine

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               3         TOP:              3.2 Chemical Events at the Synapse           MSC:   www

 

70.                Dopamine and norepinephrine are classified as:

a.

second messengers.

b.

purines.

c.

proteins.

d.

catecholamines.

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               3         TOP:              3.2 Chemical Events at the Synapse

 

71.                Insulin increases the entry of tryptophan into the brain by:

a.

weakening the blood-brain barrier.

b.

converting tryptophan into a compound that more easily enters the brain.

c.

increasing metabolic activity only in those areas of the brain that use tryptophan.

d.

causing certain competing amino acids to enter other cells, outside the brain.

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               3         TOP:              3.2 Chemical Events at the Synapse

 

72.                Acetylcholine is synthesized in the:

a.

postsynaptic terminal.

b.

presynaptic terminal.

c.

cell body.

d.

dendrites.

 

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               3         TOP:              3.2 Chemical Events at the Synapse

 

73.                The presynaptic terminal stores high concentrations of neurotransmitter molecules in:

a.

axons

b.

vesicles

c.

peptides

d.

dendrites

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

 

74.                Large neurotransmitters are synthesized in the:

a.

postsynaptic terminal.

b.

presynaptic terminal.

c.

cell body.

d.

dendrites.

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

75.                Although slower than an action potential, synaptic transmission is still relatively fast because:

a.

the synaptic cleft is very narrow.

b.

sodium ions are transported quickly.

c.

neurotransmitters diffuse faster than electricity.

d.

EPSPs travel faster than IPSPs.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

76.                Vesicles are located:

a.

in postsynaptic terminals.

b.

in dendrites.

c.

in presynaptic terminals.

d.

outside of the neuron in the extracellular fluid.

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

78.                The tiny packets that contain neurotransmitters in the presynaptic neuron are called:

a.

vesicles.

b.

bags.

c.

sacs.

d.

terminals.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

79.                High concentrations of all neurotransmitters, except for NO, are stored in the:

a.

presynaptic terminals.

b.

postsynaptic terminals.

c.

axon.

d.

cell body.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

 

 

80.                When an action potential reaches the end of an axon, it evokes the release of neurotransmitters by opening ____ channels in the axon terminal.

a.

chloride

b.

bicarbonate

c.

calcium

d.

oxygen

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

81.                When an action potential reaches the end of an axon, the depolarization causes what ionic movement in the presynaptic cell?

a.

sodium out of the cell

b.

lithium out of the cell

c.

iron into the cell

d.

calcium into the cell

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

82.                An action potential causes the release of neurotransmitters by:

a.

blocking potassium pores in the membrane.

b.

opening chloride pores in the membrane.

c.

blocking iron pores in the membrane.

d.

opening calcium pores in the membrane.

 

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse

OBJ:   4                    TOP:   3.2 Chemical Events at the Synapse

 

83.                The release of neurotransmitter from the presynaptic terminal is most dependent on the influx of what ion?

a.

sodium

b.

potassium

c.

chloride

d.

calcium

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse           MSC:   www

 

84.                The neuron excretes neurotransmitter through its membrane by a process called:

a.

Dale’s principle.

b.

exocytosis.

c.

endocytosis.

d.

voltage-dependent flow.

 

 

ANS:  B                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

85.                Exocytosis is the process by which neurotransmitters are:

a.

excreted into the synaptic cleft.

b.

synthesized.

c.

destroyed.

d.

secreted into synaptic vesicles.

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

86.                Given a repetitive series of action potentials in a given neuron, we can expect that:

a.

each action potential will release the same amount of neurotransmitter.

b.

later action potentials in a series will release more neurotransmitter than the first.

c.

many action potentials will fail to release any neurotransmitters at all.

d.

some action potentials will release one chemical as the neurotransmitter, and others will release other chemicals.

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

87.                What is the synaptic cleft?

a.

the gap between the presynaptic neuron and the postsynaptic neuron

b.

a packet that stores neurotransmitter molecules

c.

a subthreshold depolarization

d.

the storage location for calcium ions

 

 

 

ANS:  A                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

88.                What happens when a neurotransmitter is released by a presynaptic cell?

a.

It causes calcium to rush into the presynaptic neuron.

b.

It causes calcium to rush into the postsynaptic neuron.

c.

The neurotransmitter passively spreads across the synaptic cleft.

d.

The neurotransmitter is actively transported across the synaptic cleft.

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

89.                In general, a single neuron releases ____ neurotransmitter(s) and can respond to ____ neurotransmitter(s).

a.

one; many

b.

dozens of; only one

c.

several; only one

d.

several; many

 

 

ANS:  D                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

90.                In most cases, how many neurotransmitters can activate a postsynaptic neuron?

a.

only one neurotransmitter

b.

any neurotransmitter

c.

several transmitters, with different synapses responding to different transmitters

d.

several transmitters, which must be received simultaneously

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

91.                The main advantage of a neuron releasing more than one neurotransmitter is that:

a.

if it runs out of one, it has others.

b.

it can release different transmitters on different occasions.

c.

it can send more complex messages.

d.

it can release one from the axon’s terminal and one from another location along the axon.

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

92.                What determines the effect that a neurotransmitter has on the postsynaptic neuron?

a.

the speed the action potential traveled down the axon

b.

the number of branches of the presynaptic axon

c.

the receptors on the postsynaptic membrane

d.

the distance between the synapse and the cell body

 

 

ANS:  C                    PTS:   1                    DIF:    factual            REF:   The Sequence of Chemical Events at a Synapse           OBJ:               4         TOP:              3.2 Chemical Events at the Synapse

 

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